Diagnostic performance of cerebrospinal fluid free light chains in Lyme neuroborreliosis – a pilot study
نویسندگان
چکیده
منابع مشابه
Cerebrospinal Fluid in Lyme Neuroborreliosis
James J. Nocton,* Bradley J. Bloom,* Barbara J. Rutledge, David H. Persing, Eric L. Logigian, Christopher H. Schmid, and Allen C. Steere Divisions of Rheumatology/Immunology, Pediatric Rheumatology, and Clinical Care Research, New England Medical Center and Floating Hospital for Children, Tufts University School ofMedicine, and Division ofNeurology, Brigham and Women's Hospital, Harvard Medical...
متن کاملDiagnostic performance of cerebrospinal fluid chemokine CXCL13 and antibodies to the C6-peptide in Lyme neuroborreliosis.
OBJECTIVES The aim of this study was to evaluate the chemokine CXCL13 and C6 antibodies separately and in combination in paired serum/cerebrospinal fluid (CSF) samples in the laboratory diagnosis of Lyme neuroborreliosis (LNB). METHODS A large retrospective material with paired serum/CSF samples from 261 patients with clinically suspected LNB was investigated. Patients were divided into three...
متن کاملCerebrospinal fluid CXCL13 in Lyme neuroborreliosis and asymptomatic HIV infection
BACKGROUND It has been suggested that cerebrospinal fluid (CSF) CXCL13 is a diagnostic marker of Lyme neuroborreliosis (LNB), as its levels have been shown to be significantly higher in LNB than in several other CNS infections. Levels have also been shown to decline after treatment with intravenous ceftriaxone, but levels after treatment with oral doxycycline have previously not been studied. L...
متن کاملCerebrospinal fluid Lyme multiplex assay results are not diagnostic in horses with neuroborreliosis
BACKGROUND The accuracy of the Lyme multiplex assay for the diagnosis of neuroborreliosis in horses is unknown. HYPOTHESIS/OBJECTIVES To describe Lyme multiplex results in horses with a postmortem diagnosis of neuroborreliosis. The hypothesis was that paired serum and cerebrospinal fluid (CSF) results and a CSF : serum ratio would allow differentiation of horses with neuroborreliosis from tho...
متن کاملLyme neuroborreliosis: a diagnostic headache.
Case 1: A 4-year-old girl presented to our emergency department (ED) during the height of summer with 5 days of left-sided facial droop, which spared the forehead. The patient also complained of severe fatigue, 1 week of frontal headaches, urinary retention, intermittent erythematous rash around her eyes and behind her knees, and an increase in night terrors. Three days before admission, she wa...
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ژورنال
عنوان ژورنال: Clinical Chemistry and Laboratory Medicine (CCLM)
سال: 2019
ISSN: 1437-4331,1434-6621
DOI: 10.1515/cclm-2019-0315